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The inhibitory effect of honokiol, a natural plant product, on vestibular schwannoma cells.

Authors
  • Lee, Jong Dae
  • Lee, Jae Yong
  • Baek, Byoung Joon
  • Lee, Byung Don
  • Koh, Yoon Woo
  • Lee, Won-Sang
  • Lee, Yu-Jin
  • Kwon, Byoung-Mog
Type
Published Article
Journal
The Laryngoscope
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jan 01, 2012
Volume
122
Issue
1
Pages
162–166
Identifiers
DOI: 10.1002/lary.21781
PMID: 22057812
Source
Medline
License
Unknown

Abstract

Honokiol, a low molecular weight natural product, inhibits cell proliferation and promotes apoptosis in schwannoma cells by targeting the ERK pathway. Our data suggest that honokiol can be evaluated as a chemotherapeutic agent for VS.

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