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Inhibitory action of flurbiprofen and mopidamole on tumor lung metastasis formation in mice.

Authors
  • Mamytbeková, A
  • Rezábek, K
  • Grimová, J
  • Svobodová, J
Type
Published Article
Journal
Cancer treatment reports
Publication Date
Nov 01, 1987
Volume
71
Issue
11
Pages
1089–1090
Identifiers
PMID: 3677114
Source
Medline
License
Unknown

Abstract

Flurbiprofen, 0.25 mg/kg, administered to mice orally once daily during 3 days prior to an iv transplantation of Lewis lung carcinoma cells, protected 50%-57% of experimental animals from the formation of lung tumor colonies. With the daily dose of 1.0 mg/kg, this effect was less pronounced. Mopidamole, twice daily 90 mg/kg orally during 3 days, did not have this effect.

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