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Inhibition of learning and memory by general anesthetics.

Authors
  • Wang, Dian-Shi
  • Orser, Beverley A
Type
Published Article
Journal
Canadian Journal of Anesthesia/Journal canadien d anesthésie
Publisher
Springer-Verlag
Publication Date
Feb 01, 2011
Volume
58
Issue
2
Pages
167–177
Identifiers
DOI: 10.1007/s12630-010-9428-8
PMID: 21181566
Source
Medline
License
Unknown

Abstract

Anesthetics target different receptors and brain regions to modify the various forms of memory. In the hippocampus, extrasynaptic γ-aminobutyric acid subtype A receptors may play a particularly important role. Knowledge regarding the molecular basis of memory blockade may help to address memory disorders associated with the anesthetic state.

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