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Inhibition of HIV-1 replication in primary human T cells transduced with an intracellular anti-HIV-1 p17 antibody gene.

Authors
  • Tewari, Deepanker
  • Notkins, Abner Louis
  • Zhou, Paul
Type
Published Article
Journal
The journal of gene medicine
Publication Date
Mar 01, 2003
Volume
5
Issue
3
Pages
182–189
Identifiers
PMID: 12666184
Source
Medline
License
Unknown

Abstract

The expression of the anti-HIV-1 gag p17 scFv/Ckappa gene construct in primary human T cells renders these cells resistant to HIV-1 and points to the potential clinical usefulness of this gene construct for anti-HIV-1 gene therapy.

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