Affordable Access

Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine.

Authors
Type
Published Article
Journal
Gastroenterology
0016-5085
Publisher
Elsevier
Publication Date
Volume
124
Issue
2
Pages
377–391
Identifiers
PMID: 12557144
Source
Medline

Abstract

These findings suggest that CO attenuates postoperative ileus by inhibiting selective elements within the inflammatory cascade and by enhanced induction of the anti-inflammatory cytokine IL-10. In addition, the early and enhanced induction of HO-1 potentially amplifies the anti-inflammatory effects of the HO-1 pathway by protection from free radical stress and by increasing the tissue availability of CO directly at the sites of inflammation.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments