Influenza A virus infection of human middle ear cells in vitro.
Department of Otolaryngology, University of Miami School of Medicine, Florida, USA. [email protected]
- Published Article
- Publication Date
Oct 01, 2000
10 Pt 1
Primary cultures of human middle ear mucosal cells have been established. Two distinctly different cell culture systems have been developed: 1) middle ear epithelial cells and 2) either dedifferentiated epithelial cells or fibroblasts. Exposure of both cell types to INF A demonstrates that each can support cellular infection and viral replication. These models should be useful for studies of the pathogenesis of virus-mediated otitis media.
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This record was last updated on 01/21/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11037837