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[The influence of systemic digitalis application on intraocular pressure].

Authors
  • Hardt, B W
  • Johnen, R
  • Fahle, M
Type
Published Article
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Publication Date
Jan 01, 1982
Volume
219
Issue
2
Pages
76–79
Identifiers
PMID: 7141233
Source
Medline
Language
German
License
Unknown

Abstract

The intraocular pressure (IOP) of ten healthy subjects was measured before and after a 2-week systemic application of beta-methyldigoxin. The drug led to a highly significant decrease of IOP of on the average 2 mm Hg. The decrease was independent of the blood concentration of glycoside - at least within the therapeutic range. There was a positive correlation between IOP before digoxin application and the subsequent IOP decrease. The rate of outflow increased, but not significantly. Implications for the therapy of glaucoma are briefly discussed.

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