1Center for Human Genetic Research (L.K.B., R.J.A., A.T., R.R.F., J.B.M., J.C.F.) and Diabetes Research Center (Diabetes Unit) (L.K.B., L.M.D., J.C.F.), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114; Department of Medicine (L.K.B., L.M.D., J.C.F.), Harvard Medical School, and Department of Nutrition (P.W.F.), Harvard School of Public Health, Boston, Massachusetts 02115; Department of Medicine (L.K.B.), NorthShore University HealthSystem, Evanston, Illinois 60201; University of Chicago (L.K.B.), Pritzker School of Medicine, Chicago, Illinois 60637; The Biostatistics Center (K.A.J.), George Washington University, Rockville, Maryland 20852; Program in Medical and Population Genetics (A.T., J.B.M., C.G., J.C.F.), Broad Institute, Cambridge, Massachusetts 02142; Department of Epidemiology (D.D.), Colorado School of Public Health, University of Colorado, Denver, Colorado 80045; Division of Metabolism, Endocrinology, and Nutrition (S.E.K.), VA Puget Sound Health Care System and University of Washington, Seattle, Washington 98108; Department of Clinical Sciences (P.W.F.), Genetic and Molecular Epidemiology Unit, Lund University, SE-200 41 Malmö, Sweden; Diabetes Epidemiology and Clinical Research Section (R.L.H., W.C.K.), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014; Department of Medicine (N.M.M.), Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; Department of Medicine (A.R.S.), Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201; and Department of Nutrition (E.J.M.-D.), University of North Carolina, Gillings School of Global Public Health, Chapel Hill, North Carolina 27599.
Individual common and an aggregate of rare genetic variation in SLC30A8 are associated with measures of β-cell function in the DPP. Exploring rare variation may complement ongoing efforts to uncover the genetic influences that underlie complex diseases.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 01/13/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/24471563