[Influence on pubertal reproductive function in female rats by immune challenge in early life].
Department of Obstetrics and Gynecology, First Affiliated Hospital of Wenzhou Medical College, China. [email protected]
- Published Article
Zhonghua fu chan ke za zhi
- Publication Date
Jun 01, 2011
Immunological stress during early critical developmental windows could have long dysfunctional effects on the pubertal reproductive function. It delayed puberty onset, reduced the percentage of the normal oestrous cycles, decreased follicles reserve and increased the thickness of the theca interna which might involve the up-regulation of the local ovarian sympathetic nerve activity.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/21781586