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The influence of posture, Valsalva manoeuvre and coughing on portal hypertension in cirrhosis.

Authors
Type
Published Article
Journal
Scandinavian journal of clinical and laboratory investigation
Publication Date
Volume
39
Issue
7
Pages
665–669
Identifiers
PMID: 556537
Source
Medline
License
Unknown

Abstract

Percutaneous transhepatic catheterization of the portal venous system and pressure readings were performed in nineteen patients with cirrhosis of the liver and bleeding varices. Portal pressures were recorded in awake and mobile patients in supine, sitting and standing position, during sleep, ingestion of food, Valsalva manoeuvre and coughing. No significant differences were recorded in the different postures, during sleep or food intake. Four patients with hepatofugal portal blood flow had, however, lowest pressure in standing position. During Valsalva manoeuvre portal pressure was doubled, and it became fourfold during coughing. Elevations of this magnitude have not previously been reported. A relationship was found between portal pressure and size of varices.

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