The influence of intravascular volume expansion on cerebral blood flow and blood volume in normal rats.
- Published Article
- Publication Date
May 01, 1993
In normal brain, CBF does not change during volume expansion, in spite of an increase in CO. This contradicts earlier studies, the results of which indicate an independent role for cardiac output in CBF control. Cerebral blood volume increased in proportion to CVP, suggesting simple passive venous distention. Whether this could increase ICP and compromise cerebral perfusion remains unclear.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/8489067