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Influence of different intravenous lipid emulsions on hepatobiliary dysfunction in a rabbit model.

Authors
  • Kohl, Martina
  • Wedel, Thilo
  • Entenmann, Andreas
  • Stuttmann, Julia
  • Bendiks, Meike
  • Loff, Steffan
  • Köster, Stefan
  • Ortfeld, Stefan
  • Bos, Inge
Type
Published Article
Journal
Journal of Pediatric Gastroenterology and Nutrition
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Feb 01, 2007
Volume
44
Issue
2
Pages
237–244
Identifiers
PMID: 17255838
Source
Medline
License
Unknown

Abstract

In our animal model, the use of a lipid emulsion with a reduced amount of polyunsaturated fatty acids was not superior to a lipid emulsion based on soybean oil. Long-term application of n-3 fatty acids was associated with more extensive fibrosis. Therefore, intravenous n-3 fatty acids containing lipid preparations (fish oil) should not be used in patients for long-term TPN.

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