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[The influence of the dietary polyunsaturated fatty acids on the phagocyte's functional activity in rats].

Authors
  • Trushina, E N
  • Mustafina, O K
  • Kulakova, S N
Type
Published Article
Journal
Voprosy pitaniia
Publication Date
Jan 01, 2003
Volume
72
Issue
4
Pages
9–11
Identifiers
PMID: 12968296
Source
Medline
License
Unknown

Abstract

The influence of dietary polyunsaturated fatty acids on the superoxid anion production by peritoneal macrophages and phagocytosis by blood neutrophiles in male Wistar rats weighting 127.0 +/- 3.2 r was investigated after 3 months feeding. Rats fed isocaloric purified diets contained 24% fat representing combinations of lard, sunflower oil and fish oil (eiconol) providing the ratios of w6/w3 fatty acids equal 49.0; 6.1; 1.1. The increasing of superoxide formed by peritoneal macrophages and phagocytic activity of neutrophiles in the group received diet with the minimal ratios of w6/w3 fatty acids compared to that in rats fed diet with ratio 49.0 was noted. The increased activity of mononuclear-phagocytic system was confirmed by morphological investigation of peripheral lymphoid organs.

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