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Influence of cachexia and sarcopenia on survival in pancreatic ductal adenocarcinoma: a systematic review.

Authors
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8
  • 1 Pauls Stradins Clinical University Hospital, Riga, Latvia. , (Latvia)
  • 2 Hospital of Lithuanian University of Health Sciences Kaunas, Lithuania. , (Lithuania)
  • 3 Complexo Hospitalario Universitario de Ourense, Ourense, Spain. , (Spain)
  • 4 Department of Gastroenterology Pamukkale University, Denizli, Turkey. , (Turkey)
  • 5 Pauls Stradins Clinical University Hospital, Riga, Latvia; Faculty of Medicine, University of Latvia, Riga, Latvia. , (Latvia)
  • 6 Department of Digestive and Endocrine Surgery, Cochin Hospital, APHP, Paris, France; Faculté de Medecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, France. , (France)
  • 7 North East's Hepato-Pancreato-Biliary Centre at the Freeman Hospital, Newcastle, United Kingdom. , (United Kingdom)
  • 8 Department of Surgical Oncology, Medical and Rehabilitation Center under the Ministry of Health of Russian Federation, Moscow, Russia. Electronic address: [email protected] , (Russia)
Type
Published Article
Journal
Pancreatology
1424-3911
Publisher
Elsevier
Publication Date
Volume
15
Issue
1
Pages
19–24
Identifiers
DOI: 10.1016/j.pan.2014.11.006
PMID: 25524484
Source
Medline
Keywords
License
Unknown

Abstract

Impact of cachexia and sarcopenia on survival in pancreatic ductal adenocarcinoma is currently understudied in the available literature. Definitive association between cachexia and survival cannot be drawn from available studies, although weight loss and sarcopenic obesity might be considered as poor prognostic factors. Further prospective trials utilizing the consensus definition of cachexia and including other confounding factors are needed to investigate the impact of cachexia and sarcopenia on survival in pancreatic adenocarcinoma.

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