Infection of macrophages by Theiler's murine encephalomyelitis virus is highly dependent on their activation or differentiation state.
- Published Article
Journal of virology
- Publication Date
Nov 01, 1997
Macrophages are the main targets of Theiler's murine encephalomyelitis virus (TMEV) during persistent demyelinating infection of mice. Replication of TMEV in macrophages was previously shown to depend on their activation state. Here, we show that the quality of the serum used for culture drastically influences viral entry in RAW264.7 macrophages.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9343249