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Infection in central venous catheter led by parenteral nutrition of tumor patients

Authors
  • Wang, Dan
Type
Published Article
Journal
Infection International
Publisher
De Gruyter Open
Publication Date
Apr 10, 2018
Volume
6
Issue
4
Pages
103–107
Identifiers
DOI: 10.2478/ii-2018-0005
Source
De Gruyter
Keywords
License
Yellow

Abstract

With the wide application of parenteral nutrition (PN) and central venous catheter (CVC) in tumor patients, the relative infection led by CVC has become a common and troublesome hospital infection in clinics. During infusion, PN fluid forms a high-sugar and high-fat microenvironment around CVC, facilitating the adhesion, growth, and diffusion of pathogenic bacteria. This condition forms a bacterial biofilm (BF) consisting of one or several kinds of pathogenic bacteria. Upon formation of the film, pathogens in the BF can resist antibacterial drugs and immune cells, causing repeated infections of bacteria or fungi and endangering the lives of patients. In this article, we summarize the applications of PN, characteristics of CVC infection in tumor patients, mixed BF, and related research methods to provide reference for studies of mixed BF infection of CVC.

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