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Infection after fracture osteosynthesis - Part I.

Authors
  • Fang, Christian1
  • Wong, Tak-Man1, 2
  • Lau, Tak-Wing1
  • To, Kelvin Kw3
  • Wong, Samson Sy3
  • Leung, Frankie1, 2
  • 1 1 Department of Orthopaedics and Traumatology, Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong, China.
  • 2 3 Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma, University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
  • 3 2 Department of Microbiology, Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong, China.
Type
Published Article
Journal
Journal of orthopaedic surgery (Hong Kong)
Publication Date
January 2017
Volume
25
Issue
1
Identifiers
DOI: 10.1177/2309499017692712
PMID: 28215118
Source
Medline
Keywords
License
Unknown

Abstract

Bone and surgical site infections after osteosynthesis are notoriously difficult to manage and pose a tremendous burden in fracture management. In this article, we use the term osteosynthesis-associated infection (OAI) to refer to this clinical entity. While relatively few surgically treated fractures become infected, it is challenging to perform a rapid diagnosis. Optimal management strategies are complex and highly customized to each scenario and take into consideration the status of fracture union, the presence of hardware and the degree of mechanical stability. At present, a high level of relevant evidence is unavailable; most findings presented in the literature are based on laboratory work and non-randomized clinical studies. We present this overview of OAI in two parts: an examination of recent literature concerning OAI pathogenesis, diagnosis and classification and a review of treatment options.

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