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Infantile nephrotic syndrome with diffuse mesangial sclerosis: a disturbance of glomerular basement membrane development?

Authors
Type
Published Article
Journal
Clinical Nephrology
0301-0430
Publisher
Dustri-Verlag Dr. Karl Feistle
Publication Date
Volume
13
Issue
3
Pages
146–150
Identifiers
PMID: 7379364
Source
Medline

Abstract

Ultrastructural examinations of renal glomeruli in a case of diffuse mesangial sclerosis revealed a hitherto unknown type of alteration of the basement membranes ("cloudy pattern") which suggests a disturbance of glomerular basement membrane development as the basic mechanism which leads to therapy resistent infantile nephrotic syndrome.

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