Inductive Materials for Regenerative Engineering.
Connecticut Convergence Institute for Translation in Regenerative Engineering, University of Connecticut Health, Farmington, CT, USA.
Raymond and Beverly Sackler Center for Biological, Physical and Engineering Sciences, University of Connecticut Health, Farmington, CT, USA.
Department of Orthopedic Surgery, University of Connecticut Health, Farmington, CT, USA.
Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT, USA.
Department of Biomedical Engineering, University of Connecticut, Storrs, CT, USA.
Department of Materials Science and Engineering, University of Connecticut, Storrs, CT, USA.
Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, USA.
- Published Article
Journal of dental research
- Publication Date
Sep 01, 2021
Regenerative engineering has pioneered several novel biomaterials to treat critical-sized bone injuries. However, despite significant improvement in synthetic materials research, some limitations still exist. The constraints correlated with the current grafting methods signify a treatment paradigm shift to osteoinductive regenerative engineering approaches. Because of their intrinsic potential, inductive biomaterials may represent alternative approaches to treating critical bone injuries. Osteoinductive scaffolds stimulate stem cell differentiation into the osteoblastic lineage, enhancing bone regeneration. Inductive biomaterials comprise polymers, calcium phosphate ceramics, metals, and graphene family materials. This review will assess the cellular behavior toward properties of inductive materials.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 01/05/2022 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/33906507