Induction of pancreatic neoplasms by 2,2'-dioxopropyl-N-propylnitrosamine.
- Published Article
- Publication Date
Sep 01, 1975
A high incidence of pancreatic duct adenomas and carcinomas were induced in Syrian golden hamsters as early as 13 weeks after chronic administration of 2,2'-dioxopropyl-n-propylnitrosamine (DOPN) at a 10 mg/kg dose. In contrast to another pancreatic carcinogen, 2,2'-dihydroxy-propyl-n-propyl-nitrosamine, DOPN induced no tumors of the upper respiratory tract or kidneys, and only a few neoplasms of the lungs and liver.
Report this publication
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/1235057