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Induction of the neurokinin 1 receptor by TNFα in endometriotic tissue provides the potential for neurogenic control over endometriotic lesion growth.

Authors
  • McKinnon, Brett D
  • Evers, Jakob
  • Bersinger, Nick A
  • Mueller, Michael D
Type
Published Article
Journal
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Publication Date
Jun 01, 2013
Volume
98
Issue
6
Pages
2469–2477
Identifiers
DOI: 10.1210/jc.2013-1019
PMID: 23553861
Source
Medline
License
Unknown

Abstract

NK1R expression is induced in ectopic endometrial tissue by peritoneal TNFα. Induction of NK1R expression may permit endometriotic lesion maintenance via exposure to substance P.

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