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Induction of anti-DNA antibodies by immunization with activated lymphocytes and active chromatin.

Authors
  • Lu, L
  • Li, J
  • Wang, M
  • Wu, H
Type
Published Article
Journal
Chinese medical journal
Publication Date
Jun 01, 1998
Volume
111
Issue
6
Pages
524–526
Identifiers
PMID: 11245072
Source
Medline
License
Unknown

Abstract

Activated lymphocytes and their active chromatin could be the autoimmunogen(s) driving the anti-dsDNA antibodies. The change of chromatin's antigenicity by environmental factors and genetic background may be the common pathway to SLE pathogenesis.

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