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Induction and Catabolite Repression of β-Glucosidase Synthesis in Myceliophthora thermophila D-14 (= ATCC 48104)

Authors
  • Samir K. Roy
  • Syamal K. Raha
  • Susanta K. Dey
  • S. L. Chakrabarty
Publication Date
Aug 01, 1988
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

β-Glucosidase activity in Myceliophthora thermophila D-14 (= ATCC 48104) was inducible and was produced in culture filtrate during growth with various inducers, of which PNPG (p-nitrophenyl-β-d-glucoside) was the most efficient. Induction of β-glucosidase also occurred when the organism was grown in medium supplemented with different carbon sources. Carboxymethyl cellulose, cellobiose, and Solka-Floc were found effective for induction of enzyme biosynthesis. The addition of glucose to the culture medium severely repressed β-glucosidase synthesis, which could not be reversed by exogenous cyclic AMP or dibutyryl cyclic AMP.

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