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[Indices of lipid free-radical oxidation and of antiradical protection of the brain--the neurochemical correlates of the development of the general adaptation syndrome].

Authors
Type
Published Article
Journal
Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova
Publication Date
Volume
38
Issue
4
Pages
731–737
Identifiers
PMID: 3195233
Source
Medline
License
Unknown

Abstract

The stage of rat long-term adaptation to chronic emotional-pain stress is characterized by an increase of superoxide dismutase brain activity and superoxide-scavenging blood serum activity, accumulation of fluorescent products of free-radical oxidation, reduction of phospholipids and cholesterin contents in the brain lipid extracts. In the process of prolonged adaptation to the continuing chronic emotional-pain stress three periods are singled out, each of which with a definite correlation of characteristics of vegetative functions, behaviour, intensity of free-radical oxidation and antiradical defence.

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