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Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction.

Authors
  • Walsted, Emil Schwarz1
  • Faisal, Azmy2
  • Jolley, Caroline J3
  • Swanton, Laura L1
  • Pavitt, Matthew J1
  • Luo, Yuan-Ming4
  • Backer, Vibeke5
  • Polkey, Michael I1
  • Hull, James H6
  • 1 1 Royal Brompton Hospital.
  • 2 2 Alexandria University.
  • 3 3 King's College London.
  • 4 4 Guangzhou Medical College.
  • 5 5 Bispebjerg University Hospital.
  • 6 6 Royal Brompton Hospital and NHLI Imperial College London.
Type
Published Article
Journal
Journal of Applied Physiology
Publisher
American Physiological Society
Publication Date
Nov 02, 2017
Identifiers
DOI: 10.1152/japplphysiol.00691.2017
PMID: 29097629
Source
Medline
Keywords
License
Unknown

Abstract

Using simultaneous measurements of respiratory mechanics and diaphragm electromyography with endoscopic video we demonstrate, for the first time, increased work of breathing and respiratory neural drive in association with the development of EILO. Future detailed investigations are now needed to understand the role of upper airway closure in causing exertional dyspnea and exercise limitation.

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