Affordable Access

Increased resistance against shortening in myocardium from recipient hearts of 7 patients transplanted for dilated cardiomyopathy.

Authors
  • Vahl, C F
  • Bauernschmitt, R
  • Bonz, A
  • Herold, U
  • Amann, K
  • Ziegler, S
  • Hagl, S
Type
Published Article
Journal
The Thoracic and cardiovascular surgeon
Publication Date
Aug 01, 1993
Volume
41
Issue
4
Pages
224–232
Identifiers
PMID: 8211926
Source
Medline
License
Unknown

Abstract

A normal cross-bridge cycling rate in left-ventricular ESHF myocardium combined with a decreased capability of muscle shortening indicates the presence of a resistance against shortening localized either on the cross-bridge level or/and due to intra- and pericellular fibrosis. Left-ventricular contractile dysfunction in patients with end-stage heart failure may be related to a normal contractile apparatus contracting within an abnormal intracellular or interstitial environment.

Report this publication

Statistics

Seen <100 times