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Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction.

Authors
  • Fleming, Braden C
  • Proffen, Benedikt L
  • Vavken, Patrick
  • Shalvoy, Matthew R
  • Machan, Jason T
  • Murray, Martha M
Type
Published Article
Journal
Knee Surgery Sports Traumatology Arthroscopy
Publisher
Springer-Verlag
Publication Date
Apr 01, 2015
Volume
23
Issue
4
Pages
1161–1170
Identifiers
DOI: 10.1007/s00167-014-2932-6
PMID: 24633008
Source
Medline
License
Unknown

Abstract

Only the 1× platelet concentration improved healing over traditional ACL reconstruction. Increasing the platelet concentration from 1× to 5× in the ECM scaffold did not further improve the graft mechanical properties. The use of an ECM-platelet composite decreased the amount of cartilage damage seen after ACL surgery.

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