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Increased incidence of duodenitis in chronic renal failure.

Authors
  • Ala-Kaila, K
  • Paronen, I
  • Paakkala, T
Type
Published Article
Journal
Annals of clinical research
Publication Date
Jan 01, 1988
Volume
20
Issue
3
Pages
154–157
Identifiers
PMID: 3195978
Source
Medline
License
Unknown

Abstract

Forty-six consecutive patients with chronic renal failure (CRF) were assessed radiographically, endoscopically and histologically for duodenal inflammation. Their gastric secretion was also examined. Thirty-eight patients with non-ulcer dyspepsia served as controls. Histologically established duodenitis was more common in CRF patients than in controls. Among the non-dialyzed patients its prevalence reached 28% (9/32), while in the controls it was 5% (2/38) (p less than 0.05). The CRF patients with duodenitis had upper GI symptoms, hypersecretion of acid (p less than 0.05) and duodenal ulcer disease (p less than 0.05) more frequently compared with the CRF subjects with normal duodenal mucosa. The correlation of radiographically and endoscopically detected duodenitis with that found microscopically was poor.

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