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Increased immature hematopoietic progenitor cells CD34+/CD38dim in myelodysplasia.

Authors
  • Monreal, Mariela B1
  • Pardo, Maria L
  • Pavlovsky, Miguel A
  • Fernandez, Isolda
  • Corrado, Claudia S
  • Giere, Isabel
  • Sapia, Sandra
  • Pavlovsky, Santiago
  • 1 FUNDALEU (Foundation to Fight Leukemia) and Centro de Investigacion Clinica A. Ocampo, Buenos Aires, Argentina. [email protected] , (Argentina)
Type
Published Article
Journal
Cytometry. Part B, Clinical cytometry
Publication Date
Mar 01, 2006
Volume
70
Issue
2
Pages
63–70
Identifiers
PMID: 16470534
Source
Medline
License
Unknown

Abstract

Our study confirms that evaluation of CD38 expression pattern on HPC is an easy and reproducible test that allows evaluating the immature subset of progenitor cells. Increased immature HPC in high risk MDS and secondary AML may reflect blocked differentiation of CD34+ cells in these diseases.

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