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Increased expression of vascular endothelial growth factor and its receptors, VEGFR-1 and VEGFR-2, in medullary thyroid carcinoma.

Authors
  • Capp, Clarissa
  • Wajner, Simone Magagnin
  • Siqueira, Débora Rodrigues
  • Brasil, Beatriz Assis
  • Meurer, Luise
  • Maia, Ana Luiza
Type
Published Article
Journal
Thyroid
Publisher
Mary Ann Liebert
Publication Date
Aug 01, 2010
Volume
20
Issue
8
Pages
863–871
Identifiers
DOI: 10.1089/thy.2009.0417
PMID: 20615131
Source
Medline
License
Unknown

Abstract

The VEGF-A, VEGFR-1, and VEGFR-2 immunoreactive proteins are overexpressed in MTC lesions and might be implicated in tumor progression. It is not clear, however, if expression of these molecules provides prognostic information regarding the spread or outcome of MTC.

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