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Increased antigen and bacterial uptake in follicle associated epithelium induced by chronic psychological stress in rats.

Authors
  • Velin, A K
  • Ericson, A-C
  • Braaf, Y
  • Wallon, C
  • Söderholm, J D
Type
Published Article
Journal
Gut
Publisher
BMJ
Publication Date
Apr 01, 2004
Volume
53
Issue
4
Pages
494–500
Identifiers
PMID: 15016742
Source
Medline
License
Unknown

Abstract

These results show that the barrier function of follicle associated epithelium can be modulated, and that chronic stress enhances the uptake of luminal antigens and bacteria via the follicle associated epithelium. This can increase antigen exposure in Peyer's patches thereby having implications in the initiation of proinflammatory immune responses within the intestinal mucosa.

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