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Increased 27-hydroxycholesterol plasma level in men with low high density lipoprotein-cholesterol may circumvent their reduced cell cholesterol efflux rate

Authors
  • Nunes, Valéria S.
  • Panzoldo, Natália B.
  • Leança, Camila C.
  • Parra, Eliane S.
  • Zago, Vanessa S.
  • da Silva, Eliton J.
  • Cazita, Patrícia M.
  • Nakandakare, Edna R.
  • de Faria, Eliana C.
  • Quintão, Eder C.R.1, 2, 3, 4, 5, 6, 7
  • 1 Lipids Laboratory (LIM-10)
  • 2 Endocrinology and Metabolism Division of Hospital das Clinicas
  • 3 Faculty of Medical Sciences
  • 4 University of Sao Paulo
  • 5 Department of Clinical Pathology
  • 6 School of Medical Sciences
  • 7 State University of Campinas — UNICAMP
Type
Published Article
Journal
Clinica Chimica Acta
Publisher
Elsevier
Publication Date
Jan 01, 2014
Accepted Date
Mar 14, 2014
Identifiers
DOI: 10.1016/j.cca.2014.03.017
Source
Elsevier
Keywords
License
Unknown

Abstract

•Oxysterol concentrations were significantly lower in female than in male.•HDL-C concentration inversely correlates with 27-hydroxycholesterol levels.•Men with low HDL-C have increased 27-hydroxycholesterol plasma level.•27-Hydroxycholesterol levels with cell cholesterol efflux rate

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