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The increase in CO2 production induced by NaHCO3 depends on blood albumin and hemoglobin concentrations.

Authors
Type
Published Article
Journal
Intensive care medicine
Publication Date
Volume
26
Issue
5
Pages
558–564
Identifiers
PMID: 10923730
Source
Medline

Abstract

The importance of the release of CO2 from a bicarbonate load is dependent on the concentration of the blood non-bicarbonate buffers. It is therefore likely that the adverse effects of bicarbonate therapy linked to the CO2 generation are more important in patients with high blood albumin and hemoglobin concentrations.

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