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Inconclusive evidence for or against positive antigen selection in the shaping of human immunoglobulin E repertoires: a call for new approaches.

Authors
Type
Published Article
Journal
International Archives of Allergy and Immunology
1423-0097
Publisher
S. Karger AG
Publication Date
Volume
161
Issue
2
Pages
122–126
Identifiers
DOI: 10.1159/000345421
PMID: 23343692
Source
Medline
License
Unknown

Abstract

Current methodology is unable to define with certainty, using commonly assessed IgE repertoire sizes, whether antigen selection is or is not a major driving force in the establishment of human IgE. New approaches are needed to address this matter.

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