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In vivo antigenic variation of Campylobacter flagellin.

Authors
  • S M Logan
  • P Guerry
  • D M Rollins
  • D H Burr
  • T J Trust
Publication Date
Aug 01, 1989
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

Campylobacter coli VC167 cells producing either antigenic phase 1 (P1) or phase 2 (P2) flagellins (as determined by characteristic protein and DNA patterns) were used to infect rabbits by the removable intestinal tie-adult rabbit diarrhea (RITARD) procedure. Rabbits infected with P2 cells shed predominantly P2 cells throughout the infection; in rabbits infected with P1 cells, a transition of fecal isolates from P1 to P2 was observed.

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