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In Vitro Killing of Mycobacterium ulcerans by Acidified Nitrite

Authors
  • R. Phillips
  • S. Kuijper
  • N. Benjamin
  • M. Wansbrough-Jones
  • M. Wilks
  • A. H. J. Kolk
Publisher
American Society for Microbiology
Publication Date
Aug 01, 2004
Source
PMC
Keywords
License
Unknown

Abstract

Mycobacterium ulcerans, which causes Buruli ulcer, was exposed to acidified nitrite or to acid alone for 10 or 20 min. Killing was rapid, and viable counts were reduced below detectable limits within 10 min of exposure to 40 mM acidified nitrite. M. ulcerans is highly susceptible to acidified nitrite in vitro.

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