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Improvement of naturally aged skin with vitamin A (retinol).

Authors
  • Kafi, Reza
  • Kwak, Heh Shin R
  • Schumacher, Wendy E
  • Cho, Soyun
  • Hanft, Valerie N
  • Hamilton, Ted A
  • King, Anya L
  • Neal, Jacqueline D
  • Varani, James
  • Fisher, Gary J
  • Voorhees, John J
  • Kang, Sewon
Type
Published Article
Journal
Archives of Dermatology
Publisher
American Medical Association
Publication Date
Apr 30, 2007
Volume
143
Issue
5
Pages
606–612
Identifiers
PMID: 17515510
Source
Medline
License
Unknown

Abstract

Topical retinol improves fine wrinkles associated with natural aging. Significant induction of glycosaminoglycan, which is known to retain substantial water, and increased collagen production are most likely responsible for wrinkle effacement. With greater skin matrix synthesis, retinol-treated aged skin is more likely to withstand skin injury and ulcer formation along with improved appearance.

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