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Improvement of motor performance of HIV-positive patients under AZT therapy.

Authors
  • Arendt, G
  • Hefter, H
  • Buescher, L
  • Hilperath, F
  • Elsing, C
  • Freund, H J
Type
Published Article
Journal
Neurology
Publication Date
Apr 01, 1992
Volume
42
Issue
4
Pages
891–896
Identifiers
PMID: 1565249
Source
Medline
License
Unknown

Abstract

We performed motor tests (most rapid alternating movements [MRAMs] of index fingers and most rapid contractions [MRCs] of voluntary isometric index finger extensions) in HIV-positive patients with (group 1) and without (group 2) AZT treatment over a 6-month period. Whereas MRAMs remained uninfluenced, MRCs showed a clear improvement in the treated group and a decline in the nontreated group, according to the T helper cell counts. MRCs were not only a sensitive test procedure for detecting subclinical lesions in HIV-positive patients, but also a reliable therapy control measurement.

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