Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Improved production of fatty alcohols in cyanobacteria by metabolic engineering.

Authors
  • Yao, Lun
  • Qi, Fengxia
  • Tan, Xiaoming
  • Lu, Xuefeng
Type
Published Article
Journal
Biotechnology for Biofuels
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2014
Volume
7
Pages
94–94
Identifiers
DOI: 10.1186/1754-6834-7-94
PMID: 25024742
Source
Medline
Keywords
License
Unknown

Abstract

The highest yield of fatty alcohols was achieved in cyanobacteria by expressing the prokaryotic fatty acyl-CoA reductase Maqu_2220 and knocking-out the two key genes (sll0208 and sll0209) that are involved in the alka(e)ne biosynthesis pathway. Maqu_2220 was demonstrated as a robust enzyme for producing fatty alcohols in cyanobacteria. The production of fatty alcohols could be significantly increased by blocking the hydrocarbon biosynthesis pathway.

Report this publication

Statistics

Seen <100 times