Affordable Access

deepdyve-link
Publisher Website

The importance of detecting anti-DFS70 in routine clinical practice: comparison of different care settings.

Authors
  • Bonroy, Carolien1
  • Schouwers, Sofie2
  • Berth, Mario3
  • Stubbe, Muriel4
  • Piette, Yves5
  • Hoffman, Ilse6
  • Devreese, Katrien7
  • Van Hoovels, Lieve8
  • 1 Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium, Phone: +0032-9-3323631, Fax: +0032-9-3324985. , (Belgium)
  • 2 Department of Laboratory Medicine, GZA Hospitals, Antwerp, Belgium. , (Belgium)
  • 3 Immunology Department, Algemeen Medisch Laboratorium (AML), Antwerp, Belgium. , (Belgium)
  • 4 Department of Rheumatology, OLV Hospital, Aalst, Belgium. , (Belgium)
  • 5 Department of Rheumatology, Ghent University Hospital, Ghent, Belgium. , (Belgium)
  • 6 Department of Rheumatology, GZA Hospitals, Antwerp, Belgium. , (Belgium)
  • 7 Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium. , (Belgium)
  • 8 Department of Laboratory Medicine, OLV Hospital, Aalst, Belgium. , (Belgium)
Type
Published Article
Journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Publisher
Walter de Gruyter GmbH
Publication Date
Jun 27, 2018
Volume
56
Issue
7
Pages
1090–1099
Identifiers
DOI: 10.1515/cclm-2017-0541
PMID: 29427547
Source
Medline
Keywords
License
Unknown

Abstract

Anti-DFS70 prevalence depends on the applied assay and care setting. Our data suggest that, for an ANA-IIF-positive patient, it is rather the absence of AARD-associated ANA and clinical symptoms that contribute to the exclusion of AARD than the presence of anti-DFS70. Nevertheless, isolated anti-DFS70 helps to clarify positive ANA-IIF results, especially if pretest probability for AARD is low.

Report this publication

Statistics

Seen <100 times