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Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder.

Authors
  • Cadenhead, K S
  • Geyer, M A
  • Braff, D L
Type
Published Article
Journal
The American journal of psychiatry
Publication Date
Dec 01, 1993
Volume
150
Issue
12
Pages
1862–1867
Identifiers
PMID: 8238643
Source
Medline
License
Unknown

Abstract

This pattern of changes in amplitude and latency of the startle response suggests that subjects with schizotypal personality disorder perceive the prepulse stimuli but still demonstrate deficient sensorimotor gating of amplitude. These findings support the importance of startle prepulse inhibition and startle habituation as biological markers for schizophrenia spectrum disorders.

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