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Impaired fibrous repair: a possible contributor to atherosclerotic plaque vulnerability in patients with type II diabetes.

Authors
Type
Published Article
Journal
Arteriosclerosis Thrombosis and Vascular Biology
1524-4636
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Volume
34
Issue
9
Pages
2143–2150
Identifiers
DOI: 10.1161/ATVBAHA.114.303414
PMID: 25035341
Source
Medline
Keywords
License
Unknown

Abstract

This study suggests that atherosclerotic plaques in subjects with DM II are more prone to rupture because of impaired repair responses rather than to increased vascular inflammation. Although this study did not have a mechanistic design, our findings suggest that targeting impaired repair responses in carotid plaques may help to increase our understanding of atherosclerotic plaque development and vulnerability in patients with DM II.

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