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Impact of time-of-flight on PET tumor detection.

Authors
  • Kadrmas, Dan J
  • Casey, Michael E
  • Conti, Maurizio
  • Jakoby, Bjoern W
  • Lois, Cristina
  • Townsend, David W
Type
Published Article
Journal
Journal of Nuclear Medicine
Publisher
Society of Nuclear Medicine
Publication Date
Aug 01, 2009
Volume
50
Issue
8
Pages
1315–1323
Identifiers
DOI: 10.2967/jnumed.109.063016
PMID: 19617317
Source
Medline
License
Unknown

Abstract

Time-of-flight PET provides a significant improvement in observer performance for detecting focal warm lesions in a noisy background. These improvements in image quality can be expected to improve performance for the clinical tasks of detecting lesions and staging disease. Further study in a large clinical population is warranted to assess the benefit of TOF for various patient sizes and count levels, and to demonstrate effective performance in the clinical environment.

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