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Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology.

Authors
  • Cantara, Silvia1
  • Capezzone, Marco
  • Marchisotta, Stefania
  • Capuano, Serena
  • Busonero, Giulia
  • Toti, Paolo
  • Di Santo, Andrea
  • Caruso, Giuseppe
  • Carli, Anton Ferdinando
  • Brilli, Lucia
  • Montanaro, Annalisa
  • Pacini, Furio
  • 1 Section of Endocrinology and Metabolism, Department of Internal Medicine, Endocrinology, and Metabolism and Biochemistry, University of Siena, Policlinico Santa Maria alle Scotte, Viale Bracci 1, 53100 Siena, Italy. , (Italy)
Type
Published Article
Journal
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Publication Date
Mar 01, 2010
Volume
95
Issue
3
Pages
1365–1369
Identifiers
DOI: 10.1210/jc.2009-2103
PMID: 20130073
Source
Medline
License
Unknown

Abstract

Our findings demonstrate that molecular analysis of cytological specimens is feasible and that its results in combination with cytology improves the diagnostic performance of traditional cytology.

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