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Impact of Norepinephrine Weight-Based Dosing Compared With Non-Weight-Based Dosing in Achieving Time to Goal Mean Arterial Pressure in Obese Patients With Septic Shock.

Authors
  • Vadiei, Nina1
  • Daley, Mitchell J1
  • Murthy, Manasa S2
  • Shuman, Carrie S1
  • 1 1 University Medical Center Brackenridge, Austin, TX, USA.
  • 2 2 Seton Medical Center Williamson, Round Rock, TX, USA.
Type
Published Article
Journal
Annals of Pharmacotherapy
Publisher
SAGE Publications
Publication Date
Mar 01, 2017
Volume
51
Issue
3
Pages
194–202
Identifiers
DOI: 10.1177/1060028016682030
PMID: 27886982
Source
Medline
Keywords
License
Unknown

Abstract

WBD of norepinephrine does not achieve time to goal MAP earlier in obese patients with septic shock. However, WBD may lead to higher norepinephrine cumulative dose requirements and prolonged time until norepinephrine discontinuation.

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