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Impact of MRCP findings on the management of biliary strictures in post-living donor liver transplant

Authors
  • Abdelgawad, Mohamed Saied
  • Aly, Rasha Abdelhafiz
  • Sherif, Ahmed Elshawadfy
Type
Published Article
Journal
Egyptian Journal of Radiology and Nuclear Medicine
Publisher
Springer Berlin Heidelberg
Publication Date
Sep 06, 2019
Volume
50
Issue
1
Identifiers
DOI: 10.1186/s43055-019-0013-z
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundBiliary strictures are a well-recognized complication of liver transplant. Magnetic resonance cholangiopancreatography (MRCP) is the imaging modality of choice for the diagnosis of post-liver transplant biliary strictures because of its high rate of diagnostic accuracy and limited risk of complications. The purpose of this study was to assess the potential role of MRCP in the diagnosis and management of biliary strictures following living donor liver transplantation (LDLT). Data were retrospectively collected from recipients who had developed biliary stricture following living donor liver transplantation. Informed consent was signed by the patients. All patients were subjected to a proper assessment of history and clinical examination as well as routine laboratory investigations. MRCP was performed to diagnose biliary strictures and to follow cases after management.ResultsAnalysis involved 32 liver transplant recipients as 28 had anastomotic biliary stricture, 2 had intrahepatic biliary stricture, and 2 had both types (mixed biliary stricture). Management was done in 20 patients by endoscopic therapy and 4 patients by surgical therapy, while 8 patients were exposed only for long-term follow-up. Satisfactory improvement of the biliary stricture was noted in about 16 with endoscopic therapy and 2 with surgical therapy.ConclusionMRCP is a reliable non-invasive imaging modality for evaluating the biliary stricture following LDLT providing important information on its management.

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