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Impact of Ketamine Use on Adjunctive Analgesic and Sedative Medications in Critically Ill Trauma Patients.

Authors
  • Pruskowski, Kaitlin A1
  • Harbourt, Kelly2
  • Pajoumand, Mehrnaz1
  • Chui, Sai-Ho Jason1
  • Reynolds, H Neal1
  • 1 University of Maryland Medical Center.
  • 2 Notre Dame of Maryland University School of Pharmacy, University of Maryland Medical Center.
Type
Published Article
Journal
Pharmacotherapy
Publication Date
Oct 10, 2017
Identifiers
DOI: 10.1002/phar.2042
PMID: 29023898
Source
Medline
Keywords
License
Unknown

Abstract

Although the use of ketamine in critically ill, mechanically ventilated, adult trauma patients was associated with decreased opioid use, it was also associated with increased use of dexmedetomidine and ziprasidone to achieve and maintain sedation. Further examination of clinical outcomes associated with these differences in drug use in a larger population of trauma patients is warranted before routine use of ketamine for analgesia and sedation can be recommended. This article is protected by copyright. All rights reserved.

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