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Impact of hypertonic and hyperoncotic saline solutions on ischemia-reperfusion injury in free flaps.

Authors
Type
Published Article
Journal
Plastic & Reconstructive Surgery
0032-1052
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
122
Issue
1
Pages
85–94
Identifiers
DOI: 10.1097/PRS.0b013e31817743a1
PMID: 18594390
Source
Medline
License
Unknown

Abstract

The authors conclude that local administration with hypertonic saline and dextran-70 improves microcirculatory disturbances on reperfusion and increases overall free flap survival. These data demonstrate that a positive influence on no-reflow mechanisms is possible by extensive fluid shifts on the level of the microcirculation.

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