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Immunotherapy in two foals with combined immunodeficiency, resulting in graft versus host reaction.

Authors
  • Ardans, A A
  • Trommershausen-Smith, A
  • Osburn, B I
  • Mayhew, I G
  • Trees, C
  • Park, M I
  • Sawyer, M
  • Stabenfeldt, G H
Type
Published Article
Journal
Journal of the American Veterinary Medical Association
Publication Date
Jan 15, 1977
Volume
170
Issue
2
Pages
167–175
Identifiers
PMID: 13055
Source
Medline
License
Unknown

Abstract

Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.

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