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[Immunological aspects of acute renal insufficiency].

Authors
  • Pécoud, A
Type
Published Article
Journal
Schweizerische medizinische Wochenschrift
Publication Date
Apr 26, 1986
Volume
116
Issue
17
Pages
538–541
Identifiers
PMID: 3520807
Source
Medline
License
Unknown

Abstract

Uremic patients are known to be particularly susceptible to infections and possibly cancer. They have a definite cutaneous anergy to the various antigens used to test delayed-type hypersensitivity. However, in vitro investigations of the individual functions involved in the immune response have not disclosed a profound and reproducible defect of one of these functions. This could be due to the heterogeneity of the patients studied (uremia of differing etiology, variation in metabolic and nutritional conditions, and influence of multiple complications). It is also possible that the main defect lies in regulation and cooperation between the individual functions.

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